The Epilepsy-Cog study: methods to establish a harmonized study of late-onset epilepsy in a meta-cohort of six population-based cohorts in the United States
The Epilepsy-Cog pooled cohort of 43,753 participants with and without epilepsy, combined with harmonized demographic, VRFs, and event data, offers a unique resource to yield new insights into LOE.
Authors
- Adam M. Brickman (ORCID: https://orcid.org/0000-0002-5125-8226)
- Sylwia Misiewicz
- Alden L. Gross (ORCID: https://orcid.org/0000-0002-4678-0562)
- Eric Huang (ORCID: https://orcid.org/0000-0002-6444-1708)
- James Francis Burke (ORCID: https://orcid.org/0000-0002-2296-1588)
- Cheng‐Shiun Leu (ORCID: https://orcid.org/0000-0002-0301-8316)
- Hyunmi Choi
- Danurys Sanchez (ORCID: https://orcid.org/0000-0001-8273-0952)
- José Gutierrez (ORCID: https://orcid.org/0000-0002-2175-8078)
- Ligong Chen
- Kevin Strobino
- Sofia Maia (ORCID: https://orcid.org/0000-0003-1837-8258)
- Oluwadamilola Obalana
- Jiying Han
- Mitchell S.V. Elkind
- Evan L. Thacker
- Emily L Johnson
- Carolyn W. Zhu
- Minghua Liu
- Brian C Petersen
- Richard Mayeux
- Stefany Diaz Andino
- Christopher Gonzalez Corona
- W. T. Longstreth
- Mary Lou Bigg
- Tian Wang
- Emily N Briceno
- W. Craig Johnson
- Annette L Fitzpatrick
- Tatjana Rundek
- Steven J Shea
Institutions
- Brigham Young University (US)
- American Heart Association (US)
- Cedars-Sinai Medical Center (US)
- Johns Hopkins University (US)
- University of Miami (US)
- Rosalind Franklin University of Medicine and Science (US)
- University of Washington (US)
- Cornell University (US)
- University of Michigan (US)
- University of Alabama at Birmingham (US)
- Columbia University (US)
- Icahn School of Medicine at Mount Sinai (US)
Publication Details
- Journal
- medRxiv
- Published
- 2026-02-02
- DOI
- https://doi.org/10.64898/2026.01.30.26345233
- Primary Topic
- Epilepsy research and treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- U.S. Department of Health and Human Services
- National Institutes of Health
- National Institute on Aging
- National Heart, Lung, and Blood Institute
- National Institute of Neurological Disorders and Stroke
- National Center for Advancing Translational Sciences