Overlapping Yet Distinct Functions of Vacuole Membrane Protein 1 and Transmembrane Protein 41B in Modulating Hepatic Lipoprotein Secretion and Autophagy
Loss of hepatic VMP1 or TMEM41B reduces VLDL secretion and promotes MASLD via overlapping but distinct mechanisms that regulate lipoprotein secretion and autophagy.
Authors
- Ni Hong-Min
- Khue Nguyen (ORCID: https://orcid.org/0009-0001-3820-168X)
- Xiaochen Yu
- Wanqing Liu
- Yan Xie
- Mengwei Niu
- Xiaoxiao Jiang
- Allen Chen
- Wen-Xing Ding
- Nicholas O. Davidson
Institutions
- Wayne State University (US)
- Washington University in St. Louis (US)
- University of Kansas Medical Center (US)
Publication Details
- Journal
- Cellular and Molecular Gastroenterology and Hepatology
- Published
- 2026-02-01
- DOI
- https://doi.org/10.1016/j.jcmgh.2026.101751
- Citations
- 1
- Primary Topic
- Autophagy in Disease and Therapy
- Type
- article
- Field-Weighted Citation Impact
- 31.52