Integration of gut microbiota, Stroke Dysbiosis Index, and inflammatory biomarkers in assessing prognosis of acute ischemic stroke
Gut dysbiosis, elevated dysbiosis indices, and inflammatory biomarker derangements were strongly associated with post-stroke infections and adverse prognosis. Integrating microbiota and biomarker profiles with clinical parameters may provide a robust framework for risk stratification and open avenues for microbiota-targeted therapies in AIS.
Authors
- Stefan Kiechl
- Gregor Broessner
- Aryati Aryati (ORCID: https://orcid.org/0000-0001-9055-0177)
- Weny Rinawati (ORCID: https://orcid.org/0000-0001-8903-6074)
- Abdulloh Machin (ORCID: https://orcid.org/0000-0003-0369-0898)
Institutions
- Innsbruck Medical University (AT)
- Universität Innsbruck (AT)
- Universitas Airlangga (ID)
- National Australia Bank (AU)
- Stroke Association (GB)
- Universitas Dr. Soetomo (ID)
- National Brain Research Centre (IN)
Publication Details
- Journal
- Frontiers in Medicine
- Published
- 2026-02-02
- DOI
- https://doi.org/10.3389/fmed.2025.1707253
- Primary Topic
- Gut microbiota and health
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Lembaga Pengelola Dana Pendidikan