A network meta-analysis of randomized controlled trials evaluating the evidence of pharmacological agents and growth factors in the regeneration of bony defects in chronic periodontitis
The study provides clinically relevant evidence supporting the adjunctive use of pharmacologic agents with PRF to optimize regenerative outcomes. Such combinations can improve bone fill and attachment gain, offering predictable benefits for patients with chronic periodontitis.
Authors
- Shivani Sanjay Koli
- Sakshi Kotecha
- Abhay Kolte
- Surekha Rathod
- Priyanka Jaiswal
Institutions
- Maharashtra University of Health Sciences (IN)
- Datta Meghe Institute of Higher Education and Research (IN)
Publication Details
- Journal
- BMC Oral Health
- Published
- 2026-02-03
- DOI
- https://doi.org/10.1186/s12903-026-07742-8
- Primary Topic
- Oral microbiology and periodontitis research
- Type
- article
- Field-Weighted Citation Impact
- 0.00