Thrombin generation and thrombin dynamics are associated with recurrent venous thromboembolism after anticoagulation withdrawal
Reduced ETP, TM sensitivity, and thrombin inactivation were associated with VTE recurrence in people with unprovoked VTE. These biomarkers may have potential to identify patients at higher risk of recurrence.
Authors
- Geke C. Poolen (ORCID: https://orcid.org/0000-0003-4520-9732)
- Mark R. Roest
- Roger E.G. Schutgens
- Rolf T. Urbanus
- Bas de Laat
- Romy M.W. de Laat-Kremers
- Geert-Jan Geersing
Institutions
- Utrecht University (NL)
- University Medical Center Utrecht (NL)
- Synapse (Netherlands) (NL)
Publication Details
- Journal
- Journal of Thrombosis and Haemostasis
- Published
- 2026-02-03
- DOI
- https://doi.org/10.1016/j.jtha.2026.01.005
- Primary Topic
- Blood Coagulation and Thrombosis Mechanisms
- Type
- article
- Field-Weighted Citation Impact
- 0.00