Rare Case of Penile Metastasis in Prostate Carcinoma Following Radical Prostatectomy on 68Ga-PSMA PET/CT

Prostate-specific membrane antigen (PSMA) PET/CT has emerged as a sensitive and specific imaging modality for the detection and staging of prostate cancer that facilitates detection of locoregional recurrence as well as distant metastases more accurately compared with conventional imaging. Metastatic penile involvement from prostate adenocarcinoma is extremely uncommon and can be missed, highlighting the importance of careful image interpretation. Increasingly progressive PSMA uptake on follow-up is an important marker of disease progression. We present a case of 60-year-old man with carcinoma prostate after radical prostatectomy was subjected to follow-up. PSMA PET/CT imaging revealed penile metastasis. Therefore, PSMA PET/CT plays a critical role in maximal surveillance and therapeutic planning in prostate cancer.