A Case Report on the Role of Individualized, Constitutional Homeopathic Medicine in Global Developmental Delay with Autism Spectrum Disorder

Homeopathy has been applied in various neurodevelopmental disorders, but documented cases of complete functional recovery in global developmental delay (GDD) with co-existing autism spectrum disorder (ASD) remain rare. No previously published case reports are available in the literature on individualized homeopathic management of GDD. This case emphasizes the role of individualized prescribing, incorporating antenatal maternal emotional history, in the management of such conditions.A 3-year-old boy with speech delay, poor social interaction, hyperactivity, aggression, echolalia, stereotypies and poor eye contact had baseline Vineland Social Maturity Scale (VSMS) social quotient of 56 and Indian Scale for Assessment of Autism (ISAA) score of 96 and was diagnosed with mild GDD and mild ASD per DSM-5 criteria. Homeopathic treatment comprised <i>Stramonium</i> followed by <i>Staphysagria</i>, the latter selected after considering significant antenatal maternal emotional trauma. Medicines were prescribed over 13 months, interspersed with placebo.At final follow-up, VSMS had increased to 86 (within normal range) and ISAA had decreased to 61 (below autism cut-off). The Modified Naranjo Criteria for Homeopathy (MONARCH) score was +8, indicating a probable causal relationship between the homeopathic intervention and the clinical outcome.This case demonstrates the potential of individualized constitutional homeopathic treatment, with emphasis on antenatal maternal emotional history, in achieving complete functional recovery in a child with GDD and ASD.