Altered Cerebrospinal Fluid Tryptophan–Kynurenine Pathway Metabolism in Multiple System Atrophy
MSA exhibited a significant imbalance in KYN metabolism, suggesting a shift toward inflammatory processes distinct from classic neuroinflammatory markers. © 2026 The Author(s). Movement Disorders published by Wiley Periodicals LLC on behalf of International Parkinson and Movement Disorder Society.
Authors
- Ryunosuke Nagao (ORCID: https://orcid.org/0009-0001-4412-3892)
- Yasuaki Mizutani (ORCID: https://orcid.org/0000-0002-5709-8526)
- Kazuya Kawabata (ORCID: https://orcid.org/0000-0002-8851-4377)
- Sayuri Shima
- Mizuki Ito
- Akihiro Ueda
- Hirohisa Watanabe
- Yasuhiro Maeda
- Akihiro Mouri
Institutions
- Fujita Health University (JP)
- Fujita Health University Hospital (JP)
- Fujita Health University Okazaki Medical Center
- Fujita Health University Bantane Hospital
Publication Details
- Journal
- Movement Disorders
- Published
- 2026-02-02
- DOI
- https://doi.org/10.1002/mds.70210
- Primary Topic
- Tryptophan and brain disorders
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Japan Agency for Medical Research and Development
- Japan Society for the Promotion of Science