CLDN6 Expression Plasticity in Ovarian Cancer: Insights into Therapeutic Optimization for CLDN6-Targeted Immunotherapy
CLDN6-positive ovarian cancer cells exhibit remarkable plasticity influenced by microenvironmental factors and chemotherapy, providing critical insights for understanding the biology of ovarian cancer progression and optimizing CLDN6-targeting therapy.
Authors
- Takehisa Kitazawa (ORCID: https://orcid.org/0000-0002-4958-7936)
- Takayuki Kamikawa
- Naoki Kimura (ORCID: https://orcid.org/0000-0002-6419-0443)
- Etsuko Fujii (ORCID: https://orcid.org/0000-0002-2624-2126)
- Atsuhiko Kato (ORCID: https://orcid.org/0009-0000-0555-7711)
- Chie Kato (ORCID: https://orcid.org/0000-0001-8603-3759)
- Nami Yabuki (ORCID: https://orcid.org/0009-0002-2603-974X)
- Shinichi Onishi (ORCID: https://orcid.org/0000-0003-1465-6206)
- Kenji Taniguchi (ORCID: https://orcid.org/0000-0001-5980-1943)
- Hiromichi Terashima
- Moe Yoshimoto
Institutions
- Chugai Pharma (United States) (US)
Publication Details
- Journal
- Cancer Research Communications
- Published
- 2026-02-01
- DOI
- https://doi.org/10.1158/2767-9764.crc-25-0399
- Primary Topic
- Cancer Immunotherapy and Biomarkers
- Type
- article
- Field-Weighted Citation Impact
- 0.00