Postoperative Radiotherapy May Improve Survival in Certain Patients with pN2 Non-Small Cell Lung Cancer Who Do Not Have Extranodal Extension
Although PORT did not improve OS or DFS in the matched overall cohort, it significantly reduced LRR. Subgroup analyses suggested potential benefits in patients with limited nodal burden and in those without ENE or lymphatic invasion. These findings, however, should be interpreted cautiously given small subgroup sizes and inherent limitations of retrospective design.
Authors
- Jie Xiao (ORCID: https://orcid.org/0000-0002-2320-6111)
- Seung Hyuck Jeon (ORCID: https://orcid.org/0000-0001-8227-9452)
- Cen Song (ORCID: https://orcid.org/0009-0006-3232-460X)
- Sukki Cho
- Jae Hyun Jeon
- Jin-Haeng Chung
- Kwhanmien Kim
- Sanghoon Jheon
- Hyun Jung Kim
- Yu Jung Kim
Institutions
- Seoul National University Bundang Hospital (KR)
Publication Details
- Journal
- Cancer Research and Treatment
- Published
- 2026-02-03
- DOI
- https://doi.org/10.4143/crt.2025.644
- Primary Topic
- Lung Cancer Diagnosis and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Seoul National University Bundang Hospital
- National Research Foundation
- Seoul National University
- National Research Foundation of Korea