More severe joint disease and lower patient oxygenation are associated with less corrosive in vivo synovial fluid in patients with knee osteoarthritis
For the first time, correlations between patients' characteristics clinical and an in vivo electrochemical measurement have been obtained. The results showed that patients with more severe disease and more symptoms had less corrosive synovial fluid. Moreover, this study showed lower corrosive properties of synovial fluid in patients with a history of oxygen-reducing medical conditions, highlighting the critical role of oxygen in corrosion.
Authors
- Stefano Mischler (ORCID: https://orcid.org/0000-0001-5343-912X)
- Geneviève Perrenoud
- Yueyue Bao (ORCID: https://orcid.org/0000-0003-2516-272X)
- Brigitte M. Jolles (ORCID: https://orcid.org/0000-0003-3513-7608)
- A. Igual Muñoz (ORCID: https://orcid.org/0000-0002-1372-621X)
- Baptiste Ulrich-Ischer
Institutions
- École Polytechnique Fédérale de Lausanne (CH)
- University of Lausanne (CH)
Publication Details
- Journal
- Bone and Joint Research
- Published
- 2026-02-03
- DOI
- https://doi.org/10.1302/2046-3758.152.bjr-2025-0019.r1
- Primary Topic
- Total Knee Arthroplasty Outcomes
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Science Foundation
- Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung