Peripheral alterations of mitochondrial function and mitophagy in Alzheimer's disease: from fundamental research to clinical perspectives

Collectively, the reviewed findings support mitochondrial homeostasis disruption as a core pathophysiological component of AD and a promising target for biomarker development and therapeutic intervention.

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Publication Details

Journal
Current Opinion in Neurology
Published
2026-01-29
DOI
https://doi.org/10.1097/wco.0000000000001457
Primary Topic
Alzheimer's disease research and treatments
Type
article
Field-Weighted Citation Impact
0.00
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article

Peripheral alterations of mitochondrial function and mitophagy in Alzheimer's disease: from fundamental research to clinical perspectives

M. Chami, Gaëlle Deportes, Elodie Delaquaize, Fanny Eysert
Current Opinion in Neurology
Alzheimer's disease research and treatments
article

Peripheral alterations of mitochondrial function and mitophagy in Alzheimer's disease: from fundamental research to clinical perspectives

M. Chami, Gaëlle Deportes, Elodie Delaquaize, Fanny Eysert
article en

Abstract

Collectively, the reviewed findings support mitochondrial homeostasis disruption as a core pathophysiological component of AD and a promising target for biomarker development and therapeutic intervention.

Current Opinion in NeurologyVol. 39(2)
Centre National de la Recherche Scientifique (FR), Inserm (FR), Institut de Pharmacologie Moléculaire et Cellulaire (FR)
Openalex Percentile: Top 69%
Alzheimer's disease research and treatments
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