Real-world six-month outcomes after switching from aflibercept 2 mg to aflibercept 8 mg for neovascular age-related macular degeneration

Switching to aflibercept 8 mg achieved anatomical improvements and longer treatment intervals in ~80% of nAMD cases, suggesting it may be a useful alternative to aflibercept 2 mg. However, continuation may be difficult in refractory cases requiring frequent injections before switching.

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Publication Details

Journal
Japanese Journal of Ophthalmology
Published
2026-02-03
DOI
https://doi.org/10.1007/s10384-026-01329-0
Primary Topic
Retinal Diseases and Treatments
Type
article
Field-Weighted Citation Impact
0.00
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article

Real-world six-month outcomes after switching from aflibercept 2 mg to aflibercept 8 mg for neovascular age-related macular degeneration

Ryo Matoba, Tetsuro Morita, Hiroya Kindo, Mio Hosokawa et al.
Japanese Journal of Ophthalmology
Retinal Diseases and Treatments
article

Real-world six-month outcomes after switching from aflibercept 2 mg to aflibercept 8 mg for neovascular age-related macular degeneration

Ryo Matoba, Tetsuro Morita, Hiroya Kindo, Mio Hosokawa, Yuki Morizane, Chihiro Ouchi, Junko Hayashi
article en

Abstract

Switching to aflibercept 8 mg achieved anatomical improvements and longer treatment intervals in ~80% of nAMD cases, suggesting it may be a useful alternative to aflibercept 2 mg. However, continuation may be difficult in refractory cases requiring frequent injections before switching.

Japanese Journal of Ophthalmology
Okayama University (JP)
Openalex Percentile: Top 70%
Retinal Diseases and Treatments
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