Effect of Region-of-Interest Prompting on Gemini 2.5 Pro in MRI Classification of Anterior Cruciate Ligament Injury

Despite a minor improvement in the weighted F1-score with Prompt 3, all prompts demonstrate poor overall classification performance, with low sensitivity and accuracy. The consistently overlapping confidence intervals indicate that prompt variations alone are insufficient to meaningfully enhance model performance. These findings suggest fundamental limitations in the model's ability to handle this task rather than suboptimal prompting.