Comparative Efficacy of Tulathromycin and Ceftiofur for Treating Undifferentiated BRDC and Tulathromycin Metaphylaxis in Dairy Cattle

Tulathromycin and ceftiofur demonstrated comparable efficacy for treating undifferentiated BRDC in dairy cattle under field conditions. In the metaphylaxis component, conducted during the seasonal high-PM2.5 period, the absence of clinical BRDC cases did not allow for evaluation of preventive efficacy. Nevertheless, differences in selected blood parameters were observed among injection groups and should be interpreted cautiously, warranting further investigation in studies incorporating low- and high-PM2.5 comparisons.