Disease progression and plaque composition in patients with non-obstructive coronary artery disease (THRONE): A coronary computed tomography angiography follow-up study
Rates of coronary revascularization are substantial in patients with medically managed intermediate lesions. In this selected cohort, an FFRct ≤0.80 at two-year follow-up was associated with higher plaque burden and presence of high-risk plaque composition.
Authors
- Maarten J.G. Leening (ORCID: https://orcid.org/0000-0002-4143-4839)
- Ricardo P.J. Budde (ORCID: https://orcid.org/0000-0003-3792-615X)
- Isabella Kardys (ORCID: https://orcid.org/0000-0002-2115-9745)
- Karim D. Mahmoud (ORCID: https://orcid.org/0000-0001-9830-8529)
- Paul Cummins (ORCID: https://orcid.org/0000-0003-2902-704X)
- Simran P. Sharma
- Jonathan Leipsic
- Miguel E. Lemmert
- Joost Daemen
- Alexander Hirsch
- Admir Dedic
- Nicolas M. Van Mieghem
- Kaneshka Masdjedi
- Rafael J. de Windt
Institutions
- University of British Columbia (CA)
- University of Aruba (AW)
- Amphia Ziekenhuis (NL)
- Erasmus MC Cancer Institute (NL)
- Admiraal De Ruyter Ziekenhuis (NL)
- Erasmus University Rotterdam (NL)
Publication Details
- Journal
- Journal of cardiovascular computed tomography
- Published
- 2026-02-01
- DOI
- https://doi.org/10.1016/j.jcct.2026.01.006
- Primary Topic
- Cardiac Imaging and Diagnostics
- Type
- article
- Field-Weighted Citation Impact
- 0.00