Preliminary clinical study on the synergistic effects of prebiotics and β-hydroxy-β-methylbutyrate in improving muscle function and intestinal barrier function in elderly patients with sarcopenia
HMB improves muscle function in sarcopenic elderly, prebiotics combined with HMB further enhance intestinal barrier repair and reduce inflammation, offering a promising gut-muscle-targeted nutritional strategy.
Authors
- Jialu Zhuo
- Fangjing Hong
- Ting Han
- Ning Yang
- Zhihua Qu
- Zixiang Li
Institutions
- Tongji University (CN)
- Shanghai Tenth People's Hospital (CN)
Publication Details
- Journal
- Aging Clinical and Experimental Research
- Published
- 2026-02-02
- DOI
- https://doi.org/10.1007/s40520-025-03307-x
- Primary Topic
- Muscle metabolism and nutrition
- Type
- article
- Field-Weighted Citation Impact
- 0.00