Long-term cosmetic outcome after intraoperative radiotherapy boost with low-energy X-rays in breast-conserving therapy: a pooled cohort analysis of the TARGIT-BQR and ROKSM trials

In this international pooled analysis, the cosmetic outcome after IORT boost followed by whole-breast irradiation shows a good esthetic long-term outcome. Further studies should explore factors that influence cosmetic outcomes and consider additional treatment-related parameters.

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Publication Details

Journal
Strahlentherapie und Onkologie
Published
2026-02-02
DOI
https://doi.org/10.1007/s00066-026-02506-3
Primary Topic
Breast Cancer Treatment Studies
Type
article
Field-Weighted Citation Impact
0.00
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article

Long-term cosmetic outcome after intraoperative radiotherapy boost with low-energy X-rays in breast-conserving therapy: a pooled cohort analysis of the TARGIT-BQR and ROKSM trials

Elena Sperk, Benjamin Tuschy, Sylvia Büttner, Viktoria Brück et al.
Strahlentherapie und Onkologie
Breast Cancer Treatment Studies
article

Long-term cosmetic outcome after intraoperative radiotherapy boost with low-energy X-rays in breast-conserving therapy: a pooled cohort analysis of the TARGIT-BQR and ROKSM trials

Elena Sperk, Benjamin Tuschy, Sylvia Büttner, Viktoria Brück, Uta Kraus-Tiefenbacher, Ralf Keymer, Mathias Fehr, Markus Kuther, Marc Sütterlin, Christina Kaiser, Frederik Wenz, Paulina Schimmelfennig, Katharina Fleckenstein, Christiane Reuter
article en

Abstract

In this international pooled analysis, the cosmetic outcome after IORT boost followed by whole-breast irradiation shows a good esthetic long-term outcome. Further studies should explore factors that influence cosmetic outcomes and consider additional treatment-related parameters.

Strahlentherapie und Onkologie
University of Bonn (DE), Heidelberg University (DE), University Hospital Bonn (DE), University Medical Center Freiburg (DE), University Hospital Heidelberg (DE), Kantonsspital Münsterlingen (CH), Krankenhaus Nordwest (DE), Klinikum Kassel (DE), University Medical Centre Mannheim (DE), Asklepios (DE), Kantonsspital Frauenfeld (CH)
Openalex Percentile: Top 71%
Breast Cancer Treatment Studies
DOIOpen Access PDFOpenAlex
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Long-term cosmetic outcome after intraoperative radiotherapy boost with low-energy X-rays in breast-conserving therapy: a pooled cohort analysis of the TARGIT-BQR and ROKSM trials — Elena Sperk, Benjamin Tuschy, et al. · Strahlentherapie und Onkologie (2026) | TGRS Research Map | TGRS