Duplication of the prothrombin gene is associated with a significant increase in thrombin generation
The present case demonstrated duplication of the entire prothrombin gene, associated with a significant hypercoagulable risk, a finding not previously reported in the literature.
Authors
- Hagen Bönigk
- T. Siegemund (ORCID: https://orcid.org/0000-0002-6137-8467)
- Sabine Keil
- Sirak Petros
- Katja Konn
- Kristina Schlosser
- Annelie Siegemund
Institutions
- Klinikum Magdeburg (DE)
- University Hospital Magdeburg (DE)
- Westsächsische Hochschule Zwickau (DE)
- Leipzig University (DE)
Publication Details
- Journal
- Research and Practice in Thrombosis and Haemostasis
- Published
- 2026-02-01
- DOI
- https://doi.org/10.1016/j.rpth.2026.103386
- Primary Topic
- Blood Coagulation and Thrombosis Mechanisms
- Type
- article
- Field-Weighted Citation Impact
- 0.00