Histology-specific Prognostic Impact of Microscopic Positive Surgical Margins in Renal Cell Carcinoma: Implications for Postoperative Surveillance
We looked at the presence of a microscopic margin positive for tumor after surgery for kidney cancer (KC) and its association with survival. Positive margins were associated with survival outcomes in clear-cell KC, but not in less common histological KC subtypes. Our results provide subtype-specific information on outcomes for these patients after surgery and show that further research is needed for the different KC subtypes.
Authors
- Giuseppe Garofano
- Cesare Saitta (ORCID: https://orcid.org/0009-0009-1947-084X)
- Giacomo Musso (ORCID: https://orcid.org/0000-0001-6024-7177)
- Giuseppe Rosiello (ORCID: https://orcid.org/0000-0002-4354-1582)
- Natalie Birouty (ORCID: https://orcid.org/0009-0007-0536-964X)
- Kit L. Yuen
- Kazutaka Saito
- Viraj A. Master
- Mai Dabbas
- Ithaar H. Derweesh
- Dattatraya Patil
- Francesco Montorsi
- Margaret F. Meagher
- Benjamin Baker
- Andrea Salonia
- Hajime Tanaka
- Alberto Briganti
- Yosuke Yasuda
- Alessandro Larcher
- Umberto Capitanio
- Yasuhisa Fujii
Institutions
- Emory University (US)
- Vita-Salute San Raffaele University (IT)
- Tokyo University of Science (JP)
- University of California San Diego (US)
- University of Tokyo Hospital (JP)
- IRCCS Ospedale San Raffaele (IT)
- Rush University (US)
Publication Details
- Journal
- European Urology Open Science
- Published
- 2026-02-03
- DOI
- https://doi.org/10.1016/j.euros.2026.01.009
- Primary Topic
- Renal cell carcinoma treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.00