Lariciresinol: a potent natural compound with diverse therapeutic and health benefits
Scientific research has identified lariciresinol among lignan types, which shows potential against cancer development and bacterial infections in addition to serving as an antioxidant that affects oestrogen activity while blocking inflammation. The review analyses the detailed medical and biological properties of lariciresinol. The two Brassicaceae plant genera <i>Isatis indigotica</i> and <i>Brassica oleracea</i> contain this substance, which exists in various plant types. The compound demonstrated anticancer properties through its mechanisms of stopping cancer cell multiplication and triggering programmed cell death. Recent research found that lariciresinol can block the function of the virus that causes COVID-19 by reducing its ability to enter the cells and proliferate. Lariciresinol antiviral actions have been shown to reduce RNA and viral protein production. The diverse impacts indicate that lariciresinol is a potential compound for novel health solutions and future therapeutic innovations.
Authors
- Ravi Rawat (ORCID: https://orcid.org/0000-0001-6510-1046)
- Ijaz Hussain (ORCID: https://orcid.org/0000-0002-1586-1503)
- Yusuf Tutar (ORCID: https://orcid.org/0000-0003-2613-9644)
- Mudassir Hassan (ORCID: https://orcid.org/0000-0003-2820-4454)
- Azhar Rasul
Institutions
- Recep Tayyip Erdoğan University (TR)
- Government College University, Faisalabad (PK)
- Hokkaido Pharmaceutical University (JP)
- Baba Guru Nanak University (PK)
Publication Details
- Journal
- Natural Product Research
- Published
- 2026-02-01
- DOI
- https://doi.org/10.1080/14786419.2025.2611424
- Primary Topic
- Genomics, phytochemicals, and oxidative stress
- Type
- article
- Field-Weighted Citation Impact
- 0.00