Comparative Effectiveness of Single-Dose Epidural Esketamine versus Hydromorphone in Thoracic and Upper Abdominal Surgery: A Randomized Trial
Single-dose epidural esketamine for postoperative analgesia resulted in higher hydromorphone consumption and a shorter time to first rescue analgesia compared to hydromorphone.
Authors
- Yuejiao Song (ORCID: https://orcid.org/0000-0002-7712-5827)
- Ning Huang
- Junmei Wu (ORCID: https://orcid.org/0009-0003-5616-2113)
- Weifeng Hong
- Huangwei He
- Minmin Yao
- Chao Liang
- Chengyu Wang
Institutions
- Sun Yat-sen University (CN)
- Fudan University (CN)
- Zhongshan Hospital of Xiamen University (CN)
- Zhongshan Hospital (CN)
- The First Affiliated Hospital, Sun Yat-sen University (CN)
Publication Details
- Journal
- Drug Design Development and Therapy
- Published
- 2026-02-01
- DOI
- https://doi.org/10.2147/dddt.s580521
- Primary Topic
- Anesthesia and Pain Management
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Natural Science Foundation of Shanghai