Integrative analysis of rumen microbiota and host multi-organ interactions underlying feed conversion efficiency in Hu sheep
The rumen microbiota of LFCR sheep possess highly efficient capacities for volatile fatty acid and amino acid synthesis, thereby enhancing energy utilization at its source. The resulting propionate further promotes hepatic gluconeogenesis, directly supplying energy for muscle cell growth and ultimately improving FCR. Thus, co-metabolism between rumen microbiota and the liver provides energy for muscle cell growth and is a key determinant of improved feed efficiency.
Authors
- Junhua Liu (ORCID: https://orcid.org/0000-0003-4477-7439)
- Boya Tian
- Xiaowei Jia
- Daming Sun
- Wenxi Qian
- Yuanxin Zhang
- Shengyong Mao
- Guijie Zhang
Institutions
- Nanjing Agricultural University (CN)
- Ningxia University (CN)
- Tarim University (CN)
Publication Details
- Journal
- Journal of Animal Science and Biotechnology/Journal of animal science and biotechnology
- Published
- 2026-02-03
- DOI
- https://doi.org/10.1186/s40104-025-01333-3
- Citations
- 1
- Primary Topic
- Ruminant Nutrition and Digestive Physiology
- Type
- article
- Field-Weighted Citation Impact
- 51.34
Funders
- Tarim University
- Nanjing Agricultural University
- National Key Research and Development Program of China
- Fundamental Research Funds for the Central Universities