A multicomponent intervention consisting of exercise, proteins and omega-3 supplementation to improve sarcopenia in community-dwelling older adults: Lessons learned from a 5-armed randomized controlled feasibility trial
A multicomponent intervention to treat sarcopenia showed low feasibility, moderate acceptability, and high safety. Preliminary efficacy results showed that exercise with protein supplementation may improve physical function. Adding omega-3 PUFA might offer further benefits for muscle strength and mass, but should be confirmed in larger studies. The insights and the practical challenges in the ENHANce study inform future sarcopenia intervention designs.
Authors
- Laura Vercauteren (ORCID: https://orcid.org/0000-0001-6807-9550)
- Jolan Dupont (ORCID: https://orcid.org/0000-0001-5336-2791)
- Sabine Verschueren (ORCID: https://orcid.org/0000-0003-2592-494X)
- Nadjia Amini (ORCID: https://orcid.org/0000-0003-1164-2896)
- Lenore Dedeyne (ORCID: https://orcid.org/0000-0001-6109-5216)
- Laurence Lapauw (ORCID: https://orcid.org/0000-0002-9546-8532)
- Evelien Gielen (ORCID: https://orcid.org/0000-0002-8985-1201)
- Jos U. Tournoy
- Lisa Peeters (ORCID: https://orcid.org/0009-0001-0718-8160)
Institutions
- KU Leuven (BE)
Publication Details
- Journal
- The Journal of Frailty & Aging
- Published
- 2026-02-01
- DOI
- https://doi.org/10.1016/j.tjfa.2025.100129
- Primary Topic
- Nutrition and Health in Aging
- Type
- article
- Field-Weighted Citation Impact
- 0.00