High Rates of Degenerative Changes in the Lower Spine in Calcium Pyrophosphate Deposition Disease Compared to Degenerative Disc Disease

CPPD is associated with more severe and progressive structural changes in the lower spine compared to DDD. Differentiating CPPD from DDD has clinical implications, influencing both appropriate management strategies and clinical course estimation.

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Publication Details

Journal
The Journal of Rheumatology
Published
2026-02-01
DOI
https://doi.org/10.3899/jrheum.2025-0870
Primary Topic
Spine and Intervertebral Disc Pathology
Type
article
Field-Weighted Citation Impact
0.00
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article

High Rates of Degenerative Changes in the Lower Spine in Calcium Pyrophosphate Deposition Disease Compared to Degenerative Disc Disease

Kalliopi Klavdianou, Styliani Tsiami, Philipp Sewerin, D. Kiefer et al.
The Journal of Rheumatology
Spine and Intervertebral Disc Pathology
article

High Rates of Degenerative Changes in the Lower Spine in Calcium Pyrophosphate Deposition Disease Compared to Degenerative Disc Disease

Kalliopi Klavdianou, Styliani Tsiami, Philipp Sewerin, D. Kiefer, Xenofon Baraliakos, Jona Kasfeld
article en

Abstract

CPPD is associated with more severe and progressive structural changes in the lower spine compared to DDD. Differentiating CPPD from DDD has clinical implications, influencing both appropriate management strategies and clinical course estimation.

The Journal of Rheumatology
Düsseldorf University Hospital (DE), Rheumazentrum Ruhrgebiet (DE), Heinrich Heine University Düsseldorf (DE)
Openalex Percentile: Top 71%
Spine and Intervertebral Disc Pathology
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High Rates of Degenerative Changes in the Lower Spine in Calcium Pyrophosphate Deposition Disease Compared to Degenerative Disc Disease — Kalliopi Klavdianou, Styliani Tsiami, et al. · The Journal of Rheumatology (2026) | TGRS Research Map | TGRS