Evaluation of Classical and Modified Mixing Tests: Optimized Interpretation and a Structured Algorithm for Accurate Differentiation of the Causes of <scp>aPTT</scp> Prolongation

The modified aPTT mixing test provides a reliable and practical approach for interpreting prolonged aPTT. The structured algorithm, combining the modified protocol with ΔICA, offers a systematic and clinically applicable framework for laboratory evaluation.

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Publication Details

Journal
International Journal of Laboratory Hematology
Published
2026-02-01
DOI
https://doi.org/10.1111/ijlh.70064
Primary Topic
Hemophilia Treatment and Research
Type
article
Field-Weighted Citation Impact
0.00

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article

Evaluation of Classical and Modified Mixing Tests: Optimized Interpretation and a Structured Algorithm for Accurate Differentiation of the Causes of aPTT Prolongation

Tichayapa Phojanasenee, Pornnapa Police, Phichchapha Noikongdee, Dollapak Apipongrat
International Journal of Laboratory Hematology
Hemophilia Treatment and Research
article

Evaluation of Classical and Modified Mixing Tests: Optimized Interpretation and a Structured Algorithm for Accurate Differentiation of the Causes of aPTT Prolongation

Tichayapa Phojanasenee, Pornnapa Police, Phichchapha Noikongdee, Dollapak Apipongrat
article en

Abstract

The modified aPTT mixing test provides a reliable and practical approach for interpreting prolonged aPTT. The structured algorithm, combining the modified protocol with ΔICA, offers a systematic and clinically applicable framework for laboratory evaluation.

International Journal of Laboratory Hematology
Mahidol University (TH), Phramongkutklao Hospital (TH), Ramathibodi Hospital (TH), Phramongkutklao College of Medicine
Mahidol University
Openalex Percentile: Top 73%
Hemophilia Treatment and Research
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