Novel Wide‐Spectrum Virucidal Lipid Nanoparticles (Small 7/2026)
Antiviral Nanoparticles In article number e07669, Yugo Araújo Martins, Caroline Tapparel, and co-workers present POSTAN, a novel antiviral nanoparticle built from biocompatible lipids that mimic heparan sulfate proteoglycans and viral lipid rafts. By hijacking the same pathways used by viruses, POSTAN dismantles their envelopes and blocks replication, demonstrating potent, broad-spectrum virucidal activity with strong translational potential.
Authors
- Louise Bondeelle
- Caroline Tapparel
- Fernando Chahud
- Yugo Araújo Martins
- Juliano de Paula Souza
- Francesco Stellacci
- Thais Melquiades de Lima
- Renata Fonseca Vianna Lopez
- Eurico de Arruda Neto
- Han Kang Tee
- Arnaud Charles‐Antoine Zwygart
Institutions
- University of Geneva (CH)
- Universidade de Ribeirão Preto (BR)
- Universidade de São Paulo (BR)
- Clinics Hospital of Ribeirão Preto (BR)
- École Polytechnique Fédérale de Lausanne (CH)
Publication Details
- Journal
- Small
- Published
- 2026-02-01
- DOI
- https://doi.org/10.1002/smll.72115
- Primary Topic
- RNA Interference and Gene Delivery
- Type
- article
- Field-Weighted Citation Impact
- 0.00