Daily Temporal Associations Between Use of Psychoactive Substances and Fatigue, Pain, Stress, and Depressive Symptoms in People With Multiple Sclerosis

MS symptoms and psychoactive substance use are dynamically and bidirectionally related. These findings improve understanding of how individuals with MS use substances for symptom regulation, which may lead to both beneficial and adverse outcomes.

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Publication Details

Journal
Archives of Physical Medicine and Rehabilitation
Published
2026-02-01
DOI
https://doi.org/10.1016/j.apmr.2026.01.014
Primary Topic
Multiple Sclerosis Research Studies
Type
article
Field-Weighted Citation Impact
0.00

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article

Daily Temporal Associations Between Use of Psychoactive Substances and Fatigue, Pain, Stress, and Depressive Symptoms in People With Multiple Sclerosis

Dawn M. Ehde, Jeeyeon Kim, Nora E. Fritz, Anna L. Kratz et al.
Archives of Physical Medicine and Rehabilitation
Multiple Sclerosis Research Studies
article

Daily Temporal Associations Between Use of Psychoactive Substances and Fatigue, Pain, Stress, and Depressive Symptoms in People With Multiple Sclerosis

Dawn M. Ehde, Jeeyeon Kim, Nora E. Fritz, Anna L. Kratz, Kevin N. Alschuler
article en

Abstract

MS symptoms and psychoactive substance use are dynamically and bidirectionally related. These findings improve understanding of how individuals with MS use substances for symptom regulation, which may lead to both beneficial and adverse outcomes.

Archives of Physical Medicine and Rehabilitation
Wayne State University (US), University of Washington (US), University of Michigan (US), Michigan Medicine (US)
Multiple Sclerosis Society, National Institutes of Health
Good health and well-being
Openalex Percentile: Top 71%
Multiple Sclerosis Research Studies
DOIOpen Access PDFOpenAlex
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