Molecular Identification and Evaluation of Resistance to Antifungal Drugs in <i>Candida</i> Species Isolated From Diaper Rash of Neonates

The selection of itraconazole and fluconazole-resistant isolates of <i>candida</i> among pediatric population may be a concern because <i>C. albicans</i> can be involved in invasive infections. The treatment of recurrent invasive candidiasis, needing repeated course of fluconazole or itraconazole, could be a risk factor for selecting resistant isolates. In addition, as the liposomal amphotericin B is no more commercialized in our country, a higher drug selection pressure for azoles may be expected in the future.

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Journal
Health Science Reports
Published
2026-02-01
DOI
https://doi.org/10.1002/hsr2.71767
Primary Topic
Neonatal skin health care
Type
article
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article

Molecular Identification and Evaluation of Resistance to Antifungal Drugs in Candida Species Isolated From Diaper Rash of Neonates

Sedigheh Rafiei Tabatabaei, Pegah Tamimi, Seyed Alireza Fahimzad, Fatemeh Fallah et al.
Health Science Reports
Neonatal skin health care
article

Molecular Identification and Evaluation of Resistance to Antifungal Drugs in Candida Species Isolated From Diaper Rash of Neonates

Sedigheh Rafiei Tabatabaei, Pegah Tamimi, Seyed Alireza Fahimzad, Fatemeh Fallah, Roxana Mansour Ghanaei, Abdollah Karimi, Alireza Firooz, Afagh firoozgaeean Galoogah, Dorsa Kalani, Mahsa Fattahi, Hossein Foroozan, Fariba Shirvani, Shahrzad Tabatabaee, Shahnaz Armin, Mitra Radfar
article en

Abstract

The selection of itraconazole and fluconazole-resistant isolates of <i>candida</i> among pediatric population may be a concern because <i>C. albicans</i> can be involved in invasive infections. The treatment of recurrent invasive candidiasis, needing repeated course of fluconazole or itraconazole, could be a risk factor for selecting resistant isolates. In addition, as the liposomal amphotericin B is no more commercialized in our country, a higher drug selection pressure for azoles may be expected in the future.

Health Science ReportsVol. 9(2)
University of Waterloo (CA), Children's Medical Center (IR), Imam Hossein Hospital (IR), Shahid Beheshti University of Medical Sciences (IR), Tehran University of Medical Sciences (IR)
Openalex Percentile: Top 67%
Neonatal skin health care
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