Late Bioprosthetic Valve Migration- A Rare Entity After Tavi

We present a case of hemolytic anemia due to a rare complication of late bioprosthetic valve migration, who underwent successful treatment with valve in valve transcatheter aortic valve implantation. Our patient with symptomatic moderate aortic stenosis underwent the index procedure a year ago and treated for bacteremia 3 months ago, presented with hemolytic anemia and echocardiography revealing aortic paravalvular leak. The hemolysis was attributed to Bioprosthetic valve dysfunction after a negative hematological workup. The patient's aortography revealed ventricular migration of the valve, not seen on a cardiac CT scan performed before. This was followed by a successful valve in valve transcatheter aortic valve implantation with improvements in all parameters.The improvement in reticulocyte count after successful intervention reinforces bioprosthetic valve dysfunction from late valve migration, a rare phenomenon, as the cause of hemolytic anemia. Our case shows a rare complication of the transcatheter aortic valve implantation procedure and its management with a valve in valve procedure, an indication not in guidelines yet.

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Publication Details

Journal
Advances in Clinical Medical Research and Healthcare Delivery
Published
2026-02-01
DOI
https://doi.org/10.53785/2769-2779.1365
Primary Topic
Cardiac Valve Diseases and Treatments
Type
article
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article

Late Bioprosthetic Valve Migration- A Rare Entity After Tavi

Sahej Arora, Ghazi Khan, Jeremiah Depta
Advances in Clinical Medical Research and Healthcare Delivery
Cardiac Valve Diseases and Treatments
article

Late Bioprosthetic Valve Migration- A Rare Entity After Tavi

Sahej Arora, Ghazi Khan, Jeremiah Depta
article en

Abstract

We present a case of hemolytic anemia due to a rare complication of late bioprosthetic valve migration, who underwent successful treatment with valve in valve transcatheter aortic valve implantation. Our patient with symptomatic moderate aortic stenosis underwent the index procedure a year ago and treated for bacteremia 3 months ago, presented with hemolytic anemia and echocardiography revealing aortic paravalvular leak. The hemolysis was attributed to Bioprosthetic valve dysfunction after a negative hematological workup. The patient's aortography revealed ventricular migration of the valve, not seen on a cardiac CT scan performed before. This was followed by a successful valve in valve transcatheter aortic valve implantation with improvements in all parameters.The improvement in reticulocyte count after successful intervention reinforces bioprosthetic valve dysfunction from late valve migration, a rare phenomenon, as the cause of hemolytic anemia. Our case shows a rare complication of the transcatheter aortic valve implantation procedure and its management with a valve in valve procedure, an indication not in guidelines yet.

Advances in Clinical Medical Research and Healthcare DeliveryVol. 6(1)
Reduced inequalities
Openalex Percentile: Top 70%
Cardiac Valve Diseases and Treatments
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Late Bioprosthetic Valve Migration- A Rare Entity After Tavi — Sahej Arora, Ghazi Khan, et al. · Advances in Clinical Medical Research and Healthcare Delivery (2026) | TGRS Research Map | TGRS