Serum Leptin in Youth and Young Adults With Avoidant/Restrictive Food Intake Disorder Across the Weight Spectrum

Hypoleptinemia was only evident in low-weight ARIFD and strongly correlated with BMI percentile. However, relationships with anxiety may suggest additional roles of leptin in underlying ARFID psychopathology. Findings should be replicated in larger, more representative samples.

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Publication Details

Journal
International Journal of Eating Disorders
Published
2026-02-01
DOI
https://doi.org/10.1002/eat.70043
Primary Topic
Regulation of Appetite and Obesity
Type
article
Field-Weighted Citation Impact
0.00

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article

Serum Leptin in Youth and Young Adults With Avoidant/Restrictive Food Intake Disorder Across the Weight Spectrum

Julia Gydus, Madhusmita Misra, Kamryn T. Eddy, Nadia Micali et al.
International Journal of Eating Disorders
Regulation of Appetite and Obesity
article

Serum Leptin in Youth and Young Adults With Avoidant/Restrictive Food Intake Disorder Across the Weight Spectrum

Julia Gydus, Madhusmita Misra, Kamryn T. Eddy, Nadia Micali, Stefania Yee, Lilian P. Palmer, Megan Kuhnle, Franziska Plessow, Taylor L. Rezeppa, Lauren Breithaupt, Vittoria Trolio, Jennifer J. Thomas, Kristine Hauser, Kendra R. Becker, Helen Burton‐Murray, Elizabeth A. Lawson
article en

Abstract

Hypoleptinemia was only evident in low-weight ARIFD and strongly correlated with BMI percentile. However, relationships with anxiety may suggest additional roles of leptin in underlying ARFID psychopathology. Findings should be replicated in larger, more representative samples.

International Journal of Eating Disorders
University of Geneva (CH), Harvard University (US), University of California, San Francisco (US), Massachusetts General Hospital (US), University Hospital of Geneva (CH), Ohio University (US), Institute of Child Health (IN), University College London (GB), Mass General Brigham (US), McGill University (CA), University of Virginia (US)
Massachusetts General Hospital, National Institutes of Health
Zero hunger
Openalex Percentile: Top 66%
Regulation of Appetite and Obesity
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