Mixed-Methods to Define Meaningful Change using Exit Interviewand Clinical Trial Data in Patients with Tenosynovial Giant Cell Tumor (TGCT)

The responder definitions were at least a 3-point improvement for PROMIS-PF, a 10% improvement for active ROM, and a 2-point improvement for the Worst Stiffness NRS. Qualitative interviews facilitate integrating the patient perspective in the selection of anchors and defining meaningful change.

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Publication Details

Journal
Quality of Life Research
Published
2026-02-01
DOI
https://doi.org/10.1007/s11136-026-04162-7
Primary Topic
Musculoskeletal synovial abnormalities and treatments
Type
article
Field-Weighted Citation Impact
0.00
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article

Mixed-Methods to Define Meaningful Change using Exit Interviewand Clinical Trial Data in Patients with Tenosynovial Giant Cell Tumor (TGCT)

Nicholas A. Zeringo, Hans Gelderblom, Tsion Fikre, Yipin Han et al.
Quality of Life Research
Musculoskeletal synovial abnormalities and treatments
article

Mixed-Methods to Define Meaningful Change using Exit Interviewand Clinical Trial Data in Patients with Tenosynovial Giant Cell Tumor (TGCT)

Nicholas A. Zeringo, Hans Gelderblom, Tsion Fikre, Yipin Han, William Tap, Michiel Van De Sande, Nicholas Bernthal, Christopher Tait, Brooke Harrow, Katelyn N. Cutts, Amanda Saunders, Heather L. Gelhorn
article en

Abstract

The responder definitions were at least a 3-point improvement for PROMIS-PF, a 10% improvement for active ROM, and a 2-point improvement for the Worst Stiffness NRS. Qualitative interviews facilitate integrating the patient perspective in the selection of anchors and defining meaningful change.

Quality of Life ResearchVol. 35(3)
Memorial Sloan Kettering Cancer Center (US), University of California, Los Angeles (US), Leiden University Medical Center (NL), Deciphera Pharmaceuticals (United States) (US), Gramercy Research Group (United States) (US), Thermo Fisher Scientific (Israel) (IL)
Openalex Percentile: Top 71%
Musculoskeletal synovial abnormalities and treatments
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