Inflammation-induced impairment of synaptic plasticity accelerates atherosclerosis co-depression disease: insights from bioinformatics analysis and transcriptomics
Our study identified seven candidate AS co-depression biomarkers and verified that inflammation-induced damage to synaptic plastic rows is an important mechanism of AS co-depression, providing new insights into the diagnosis and treatment of AS co-depression disorders.
Authors
- Xu Liu
- Youliang Wen
- Yuzhen Fan
- Houmin Lai
- Junjie Zhou
- Qiang Luo
- Yulong Zhao
- Peng Ren
- Renbo Zhang
- Xiaoyun Wu
Institutions
- Ganzhou People's Hospital (CN)
- Gannan Medical University (CN)
- First Affiliated Hospital of Gannan Medical University (CN)
Publication Details
- Journal
- Cell & Bioscience
- Published
- 2026-02-01
- DOI
- https://doi.org/10.1186/s13578-026-01535-w
- Primary Topic
- Tryptophan and brain disorders
- Type
- article
- Field-Weighted Citation Impact
- 0.00