Laboratory solution to diagnose and monitor atypical IgG4-mediated anti-GBM disease
Here we demonstrate proof-of-concept of a modified IgG4 anti-GBM blood test allowing serological confirmation of atypical anti-GBM disease and sensitive monitoring of therapy response.
Authors
- Rosa G.M. Lammerts
- Anne-Els van de Logt
- Mark Lenssen
- Jan-Stephan Sanders
- Ingeborg Bajema
- Mark Eijgelsheim
- Wibe Hoefsloot
- Annechien J.A. Lambeck
- Renate G. van der Molen
- Joannes F.M. Jacobs
- Wilbert A.G. van der Meijden
- Eric J. Steenbergen
Institutions
- University Medical Center Groningen (NL)
- Radboud University Nijmegen (NL)
- Radboud University Medical Center (NL)
- Radboud Institute for Molecular Life Sciences (NL)
Publication Details
- Journal
- Clinical Chemistry and Laboratory Medicine (CCLM)
- Published
- 2026-02-01
- DOI
- https://doi.org/10.1515/cclm-2025-1499
- Primary Topic
- IgG4-Related and Inflammatory Diseases
- Type
- article
- Field-Weighted Citation Impact
- 0.00