The Inflammation-Presepsin Score as a Predictor of Mortality in Elderly Sepsis Patients (≥75 Years): A Pilot Study

iPS-PI may be superior to presepsin alone as an independent predictor of mortality in extremely elderly sepsis patients. This finding strongly advocates for the use of iPS-PI as a time-sensitive "rule in" tool for early risk stratification, facilitating immediate and tailored aggressive therapeutic interventions by geriatric and critical care clinicians. iPS-PI also directly addresses the diagnostic challenges unique to geriatric sepsis management.