Association of clinicopathological characteristics and baseline peripheral blood lymphocyte subsets with efficacy of first-line immunotherapy in advanced gastric cancer

Clinicopathological characteristics and baseline peripheral lymphocyte subsets were significantly associated with efficacy of first-line chemotherapy combined with ICIs in pMMR HER2-negative advanced G/GEJC, highlighting the potential utility of integrating these accessible parameters for efficacy prediction.

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Publication Details

Journal
Discover Oncology
Published
2026-02-01
DOI
https://doi.org/10.1007/s12672-026-04444-z
Primary Topic
Cancer Immunotherapy and Biomarkers
Type
article
Field-Weighted Citation Impact
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article

Association of clinicopathological characteristics and baseline peripheral blood lymphocyte subsets with efficacy of first-line immunotherapy in advanced gastric cancer

Wenfei Li, Xiaotian Zhang, Cheng Zhang, Lin Cong et al.
Discover Oncology
Cancer Immunotherapy and Biomarkers
article

Association of clinicopathological characteristics and baseline peripheral blood lymphocyte subsets with efficacy of first-line immunotherapy in advanced gastric cancer

Wenfei Li, Xiaotian Zhang, Cheng Zhang, Lin Cong, Sai Ge, Huizhen Liu, Xiaoyi Chong, Yakun Wang, Liyang Mo
article en

Abstract

Clinicopathological characteristics and baseline peripheral lymphocyte subsets were significantly associated with efficacy of first-line chemotherapy combined with ICIs in pMMR HER2-negative advanced G/GEJC, highlighting the potential utility of integrating these accessible parameters for efficacy prediction.

Discover OncologyVol. 17(1)
Peking University (CN), Peking University Cancer Hospital (CN), Inner Mongolia Medical University (CN)
Good health and well-being
Openalex Percentile: Top 71%
Cancer Immunotherapy and Biomarkers
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