Large uterine lipoleiomyoma clinically considered as a sarcoma in a premenopausal woman: A case report and brief review of literature

• Uterine lipoleiomyomas are a rare benign tumor composed of fat and smooth muscle. • Uterine lipoleiomyomas are commonly seen in postmenopausal women. • Imaging findings of uterine lipoleiomyomas can mimic some malignant tumors like liposarcoma. • Uterine lipoleimoyomas tend to be small in size. • Histopathology is essential diagnose uterine lipoleiomyoma. Uterine lipoleiomyoma is a rare subtype of leiomyoma composed of bundles of smooth muscle and fat. The majority of cases tend to be small and are usually diagnosed incidentally in obese postmenopausal women. Hereby we presented a large uterine lipoleiomyoma in a premenopausal woman who presented with abnormal uterine bleeding. This case report highlights clinicoradiopathologic features of uterine lipoleiomyoma and briefly reviews the existing literature.

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Publication Details

Journal
Human Pathology Reports
Published
2026-02-01
DOI
https://doi.org/10.1016/j.hpr.2026.300820
Primary Topic
Uterine Myomas and Treatments
Type
article
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article

Large uterine lipoleiomyoma clinically considered as a sarcoma in a premenopausal woman: A case report and brief review of literature

Musie Negasi Gebreslase, Shunun Gidena Abrha, Tsegay Teklehaymanot Haftu, Yemane Leake Gebremichael et al.
Human Pathology Reports
Uterine Myomas and Treatments
article

Large uterine lipoleiomyoma clinically considered as a sarcoma in a premenopausal woman: A case report and brief review of literature

Musie Negasi Gebreslase, Shunun Gidena Abrha, Tsegay Teklehaymanot Haftu, Yemane Leake Gebremichael, Demelash Darota Dojamo, Seblewengel Maru Wubalem, Birhanu Kassie Reta, Melaku Abay Muluneh
article en

Abstract

• Uterine lipoleiomyomas are a rare benign tumor composed of fat and smooth muscle. • Uterine lipoleiomyomas are commonly seen in postmenopausal women. • Imaging findings of uterine lipoleiomyomas can mimic some malignant tumors like liposarcoma. • Uterine lipoleimoyomas tend to be small in size. • Histopathology is essential diagnose uterine lipoleiomyoma. Uterine lipoleiomyoma is a rare subtype of leiomyoma composed of bundles of smooth muscle and fat. The majority of cases tend to be small and are usually diagnosed incidentally in obese postmenopausal women. Hereby we presented a large uterine lipoleiomyoma in a premenopausal woman who presented with abnormal uterine bleeding. This case report highlights clinicoradiopathologic features of uterine lipoleiomyoma and briefly reviews the existing literature.

Human Pathology ReportsVol. 43
Wollo University (ET), Addis Ababa University (ET), Aksum University (ET)
Gender equality
Openalex Percentile: Top 72%
Uterine Myomas and Treatments
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