Causal Associations Between Interleukin‐13 Inhibitors and Atopic Dermatitis Related Neuropsychiatric Comorbidities

The genome-wide association study (GWAS) summary data utilized in this study are publicly available from the IEU OpenGWAS project, UK Biobank (UKB), FinnGen and Blood Cell Consortium. We acknowledge all the consortiums, investigators, and participants for making these resources available. Table S1: The IVs for downregulated IL-13 signaling proxied by decreased circulating eosinophil counts. Table S2: Overview of outcome GWAS datasets and sample overlap bias estimates. Table S3: Results of Mendelian randomization. Table S4: Heterogeneity test of Mendelian randomization. Table S5: Pleiotropy test of Mendelian randomization. Please note: The publisher is not responsible for the content or functionality of any supporting information supplied by the authors. Any queries (other than missing content) should be directed to the corresponding author for the article.

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Publication Details

Journal
Allergy
Published
2026-02-01
DOI
https://doi.org/10.1111/all.70242
Primary Topic
Dermatology and Skin Diseases
Type
article
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0.00
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article

Causal Associations Between Interleukin‐13 Inhibitors and Atopic Dermatitis Related Neuropsychiatric Comorbidities

Xingjie Hao, Danqi Li, Qi Wang, Chen Shen et al.
Allergy
Dermatology and Skin Diseases
article

Causal Associations Between Interleukin‐13 Inhibitors and Atopic Dermatitis Related Neuropsychiatric Comorbidities

Xingjie Hao, Danqi Li, Qi Wang, Chen Shen, Xiaoping Miao, Ruogu Meng, Xin Wang, Shuomin Sun, Juan Tao, Wen‐Hung Chung
article en

Abstract

The genome-wide association study (GWAS) summary data utilized in this study are publicly available from the IEU OpenGWAS project, UK Biobank (UKB), FinnGen and Blood Cell Consortium. We acknowledge all the consortiums, investigators, and participants for making these resources available. Table S1: The IVs for downregulated IL-13 signaling proxied by decreased circulating eosinophil counts. Table S2: Overview of outcome GWAS datasets and sample overlap bias estimates. Table S3: Results of Mendelian randomization. Table S4: Heterogeneity test of Mendelian randomization. Table S5: Pleiotropy test of Mendelian randomization. Please note: The publisher is not responsible for the content or functionality of any supporting information supplied by the authors. Any queries (other than missing content) should be directed to the corresponding author for the article.

Allergy
Peking University (CN), Wuhan University (CN), Linkou Chang Gung Memorial Hospital (TW), Zhongnan Hospital of Wuhan University (CN), Wuhan Union Hospital (CN), Xiamen Chang Gung Hospital (CN), Union Hospital (CN), Huazhong University of Science and Technology (CN)
Partnerships for the goals
Openalex Percentile: Top 70%
Dermatology and Skin Diseases
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Causal Associations Between Interleukin‐13 Inhibitors and Atopic Dermatitis Related Neuropsychiatric Comorbidities — Xingjie Hao, Danqi Li, et al. · Allergy (2026) | TGRS Research Map | TGRS