Health-related quality of life in patients receiving medicinal cannabis: systematic review and meta-analysis of primary research findings 2015–2025

This systematic review and meta-analyses of studies published between 2015 and 2025 found that few studies provided HRQL definitions, and a third of studies did not explain why they measured HRQL. To ensure appropriate measures are used for this important treatment outcome, future studies should define HRQL and justify the HRQL assessment in the context of research objectives. Overall, improvements in HRQL were observed across studies of patients using MC.