UGT1A6 variants and deferiprone-induced ADRs: a complication-specific analysis in Iranian thalassemia patients

Specific UGT1A6 diplotypes and sex are differentially associated with distinct deferiprone-related ADRs. A complication-specific pharmacogenetic approach can improve understanding of deferiprone-related ADRs.

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Publication Details

Journal
Pharmacogenomics
Published
2025-12-12
DOI
https://doi.org/10.1080/14622416.2025.2608573
Primary Topic
Hemoglobinopathies and Related Disorders
Type
article
Field-Weighted Citation Impact
0.00
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article

UGT1A6 variants and deferiprone-induced ADRs: a complication-specific analysis in Iranian thalassemia patients

Majid Ghanavat, Marjan Mansourian, Mansoor Salehi, Malihe Najaflu et al.
Pharmacogenomics
Hemoglobinopathies and Related Disorders
article

UGT1A6 variants and deferiprone-induced ADRs: a complication-specific analysis in Iranian thalassemia patients

Majid Ghanavat, Marjan Mansourian, Mansoor Salehi, Malihe Najaflu, Ellis J. Neufeld
article en

Abstract

Specific UGT1A6 diplotypes and sex are differentially associated with distinct deferiprone-related ADRs. A complication-specific pharmacogenetic approach can improve understanding of deferiprone-related ADRs.

PharmacogenomicsVol. 26(17-18)
Isfahan University of Medical Sciences (IR), St. Jude Children's Research Hospital (US)
Openalex Percentile: Top 23%
Hemoglobinopathies and Related Disorders
DOIOpen Access PDFOpenAlex
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UGT1A6 variants and deferiprone-induced ADRs: a complication-specific analysis in Iranian thalassemia patients — Majid Ghanavat, Marjan Mansourian, et al. · Pharmacogenomics (2025) | TGRS Research Map | TGRS