Methamphetamine regulates microglial polarization and glycolytic activity to promote Parkinson's disease through the LIPH/LPA/PI3K/AKT signaling axis
METH may promote M1 polarization and glycolytic activity in microglia by activating LIPH/LPA/PI3K/AKT signaling, thus promoting the progression of PD.
Authors
- Hao Fan
- Xin Geng
- Yanghong Zou
- Hui Bian
- Chunhai Zhang
- Yingwang Yuan
- Ailan Pang
- Jinghui Li
Institutions
- Kunming Medical University (CN)
- First Affiliated Hospital of Kunming Medical University (CN)
Publication Details
- Journal
- International Immunopharmacology
- Published
- 2026-02-01
- DOI
- https://doi.org/10.1016/j.intimp.2026.116306
- Primary Topic
- Parkinson's Disease Mechanisms and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.00