Systematic optimization for the rapid generation of high-quality online adapted proton therapy plans in a commercial treatment planning system
Online adaptive proton therapy (OAPT) requires a fast plan optimization. Different optimization parameters of a commercial treatment planning system were investigated for OAPT of locally advanced non-small cell lung-cancer patients. With the selected parameters, clinical-quality plans were optimized within a median time of 4 min, currently deemed acceptable for OAPT.
Authors
- Esther GC Troost
- Virginia Gambetta
- Albin Fredriksson
- Kristin Stützer
- Annabell Eberhardt
- Stefan Menkel
- Lena Nenoff
- Christian Richter
- Rebecca Bütof
Institutions
- Heidelberg University (DE)
- Helmholtz-Zentrum Dresden-Rossendorf (DE)
- University Hospital Heidelberg (DE)
- RaySearch Laboratories (Sweden) (SE)
- University Hospital Carl Gustav Carus (DE)
Publication Details
- Journal
- Radiotherapy and Oncology
- Published
- 2026-02-01
- DOI
- https://doi.org/10.1016/j.radonc.2026.111415
- Primary Topic
- Radiation Therapy and Dosimetry
- Type
- article
- Field-Weighted Citation Impact
- 0.00