Safety, tolerability, and pharmacokinetics of CG2001 in Chinese adult male subjects with androgenetic alopecia: a randomized, double-blind, placebo-controlled, single- and multi-doses, phase 1 clinical study

The favorable safety profile and reduced systemic finasteride exposure position CG2001 as a promising alternative, supporting further clinical development in a phase IIa trial, and provide a pharmacokinetic foundation for subsequent efficacy trials in patients with AGA.

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Publication Details

Journal
Journal of Dermatological Treatment
Published
2026-02-01
DOI
https://doi.org/10.1080/09546634.2026.2616198
Primary Topic
Hair Growth and Disorders
Type
article
Field-Weighted Citation Impact
0.00
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article

Safety, tolerability, and pharmacokinetics of CG2001 in Chinese adult male subjects with androgenetic alopecia: a randomized, double-blind, placebo-controlled, single- and multi-doses, phase 1 clinical study

Liming Chen, Binyi Hu, Hui Zhang, Meng Xiao et al.
Journal of Dermatological Treatment
Hair Growth and Disorders
article

Safety, tolerability, and pharmacokinetics of CG2001 in Chinese adult male subjects with androgenetic alopecia: a randomized, double-blind, placebo-controlled, single- and multi-doses, phase 1 clinical study

Liming Chen, Binyi Hu, Hui Zhang, Meng Xiao, Qun Gu, Ziyan Ding, Wenyan Zhao, Cheng Zhou, Shuang Li, Fan Huang, Yanting Li, Jianzhong Zhang, Qian Wang, Rui Ding, Suping Niu, Jiaojiao Zhang, Yian Liu, Yi Fang, Baohui Yu, Fang Men, Jianzhong Zhang
article en

Abstract

The favorable safety profile and reduced systemic finasteride exposure position CG2001 as a promising alternative, supporting further clinical development in a phase IIa trial, and provide a pharmacokinetic foundation for subsequent efficacy trials in patients with AGA.

Journal of Dermatological TreatmentVol. 37(1)
Xuzhou Medical College (CN), Peking University (CN), National Institutes of Pharmaceutical Research and Development (China) (CN), Peking University People's Hospital (CN)
Good health and well-being
Openalex Percentile: Top 72%
Hair Growth and Disorders
DOIOpen Access PDFOpenAlex
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Safety, tolerability, and pharmacokinetics of CG2001 in Chinese adult male subjects with androgenetic alopecia: a randomized, double-blind, placebo-controlled, single- and multi-doses, phase 1 clinical study — Liming Chen, Binyi Hu, et al. · Journal of Dermatological Treatment (2026) | TGRS Research Map | TGRS