Feedback control of excitability and high K <sup>+</sup> induced epileptiform bursts in male rat hippocampal slices with a photocaged adenosine A <sub>1</sub> receptor agonist
Combining photopharmacological adenosinergic modulation with real-time field potential monitoring provides a first step towards closed-loop precision treatment for diseases related to neuronal hyperexcitability, such as epilepsy.
Authors
- Evelien Carrette
- Marijke Vergaelen
- Paul Boon
- Kristl Vonck
- Erine Craey
- Wytse J. Wadman
- Jeroen Spanoghe
- Robrecht Raedt
- Serge Van Calenbergh
Institutions
- HOGENT University of Applied Sciences and Arts (BE)
- Ghent University Hospital (BE)
- Ghent University (BE)
Publication Details
- Journal
- British Journal of Pharmacology
- Published
- 2026-02-01
- DOI
- https://doi.org/10.1111/bph.70349
- Primary Topic
- Neuroscience and Neuropharmacology Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Fonds Wetenschappelijk Onderzoek
- Universiteit Gent
- Vlaamse regering
- Bijzonder Onderzoeksfonds UGent