Relaxivity of Gadobutrol and Gadoteric Acid in Cerebrospinal Fluid at <scp>3</scp> T

The relaxivity was higher in CSF than in the isotonic solution, particularly for gadobutrol. Systematic differences in relaxivity between scanners may potentially be corrected using a scaling factor derived from the T1 time of baseline CSF. For CSF studies using T1 mapping with a gadolinium-based contrast agent, we recommend using a CSF-specific relaxivity constant.

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Publication Details

Journal
Magnetic Resonance in Medicine
Published
2026-02-01
DOI
https://doi.org/10.1002/mrm.70284
Primary Topic
Cerebrospinal fluid and hydrocephalus
Type
article
Field-Weighted Citation Impact
0.00

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article

Relaxivity of Gadobutrol and Gadoteric Acid in Cerebrospinal Fluid at 3 T

Anders Garpebring, Anders Wåhlin, Anders Eklund, Sofia Behndig et al.
Magnetic Resonance in Medicine
Cerebrospinal fluid and hydrocephalus
article

Relaxivity of Gadobutrol and Gadoteric Acid in Cerebrospinal Fluid at 3 T

Anders Garpebring, Anders Wåhlin, Anders Eklund, Sofia Behndig, Jan Malm, Daniel Dahlgren Lindström
article en

Abstract

The relaxivity was higher in CSF than in the isotonic solution, particularly for gadobutrol. Systematic differences in relaxivity between scanners may potentially be corrected using a scaling factor derived from the T1 time of baseline CSF. For CSF studies using T1 mapping with a gadolinium-based contrast agent, we recommend using a CSF-specific relaxivity constant.

Magnetic Resonance in Medicine
Umeå University (SE)
Vetenskapsrådet, Stiftelsen för Strategisk Forskning
Openalex Percentile: Top 72%
Cerebrospinal fluid and hydrocephalus
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