Comparison of the Sedative, Recovery, and Analgesic Effects of Oral Dexmedetomidine, Ketamine, and Midazolam for Premedication in Children Undergoing Inguinal Hernia Surgery: A Randomized Double-Blind Study

Oral dexmedetomidine, ketamine, and midazolam provided comparable sedation quality and parental separation ease in children undergoing inguinal hernia surgeries. However, dexmedetomidine showed significant advantages by reducing recovery time and improving postoperative pain scores, despite a higher incidence of bradycardia in some patients. Thus, oral dexmedetomidine appears to be an efficient and safe alternative for pediatric premedication, provided careful heart rate monitoring.

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Publication Details

Journal
Anesthesiology and Pain Medicine
Published
2025-12-31
DOI
https://doi.org/10.5812/aapm-166505
Primary Topic
Anesthesia and Sedative Agents
Type
article
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article

Comparison of the Sedative, Recovery, and Analgesic Effects of Oral Dexmedetomidine, Ketamine, and Midazolam for Premedication in Children Undergoing Inguinal Hernia Surgery: A Randomized Double-Blind Study

Mohamed Zakarea Wfa, Laila Ahmed Elahwal, Hadal Hassan Mohsen, Motaz Amr Abu Sabaa
Anesthesiology and Pain Medicine
Anesthesia and Sedative Agents
article

Comparison of the Sedative, Recovery, and Analgesic Effects of Oral Dexmedetomidine, Ketamine, and Midazolam for Premedication in Children Undergoing Inguinal Hernia Surgery: A Randomized Double-Blind Study

Mohamed Zakarea Wfa, Laila Ahmed Elahwal, Hadal Hassan Mohsen, Motaz Amr Abu Sabaa
article en

Abstract

Oral dexmedetomidine, ketamine, and midazolam provided comparable sedation quality and parental separation ease in children undergoing inguinal hernia surgeries. However, dexmedetomidine showed significant advantages by reducing recovery time and improving postoperative pain scores, despite a higher incidence of bradycardia in some patients. Thus, oral dexmedetomidine appears to be an efficient and safe alternative for pediatric premedication, provided careful heart rate monitoring.

Anesthesiology and Pain MedicineVol. 15(6)
Ain Shams University (EG), Tanta University (EG)
Good health and well-being
Openalex Percentile: Top 21%
Anesthesia and Sedative Agents
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