Nivolumab plus ipilimumab versus lenvatinib or sorafenib as first‐line treatment for unresectable hepatocellular carcinoma: A cost‐effectiveness analysis

Nivolumab plus ipilimumab is unlikely to be cost-effective as first-line therapy for unresectable HCC from US health care payer perspective. However, extended dosing interval or price reductions may render the regimen economically viable, with important implications for clinical practice, payers, and policy.

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Publication Details

Journal
Cancer
Published
2026-02-01
DOI
https://doi.org/10.1002/cncr.70259
Primary Topic
Hepatocellular Carcinoma Treatment and Prognosis
Type
article
Field-Weighted Citation Impact
0.00
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article

Nivolumab plus ipilimumab versus lenvatinib or sorafenib as first‐line treatment for unresectable hepatocellular carcinoma: A cost‐effectiveness analysis

Zhengxiong Li, Wensheng Liu, Junbo Ge, Jiefeng Luo et al.
Cancer
Hepatocellular Carcinoma Treatment and Prognosis
article

Nivolumab plus ipilimumab versus lenvatinib or sorafenib as first‐line treatment for unresectable hepatocellular carcinoma: A cost‐effectiveness analysis

Zhengxiong Li, Wensheng Liu, Junbo Ge, Jiefeng Luo, Lu Han, Qiong Du, Sizhen Cai, Chengxia Gui, Xinyi Mo
article en

Abstract

Nivolumab plus ipilimumab is unlikely to be cost-effective as first-line therapy for unresectable HCC from US health care payer perspective. However, extended dosing interval or price reductions may render the regimen economically viable, with important implications for clinical practice, payers, and policy.

CancerVol. 132(3)
Shanghai Medical College of Fudan University (CN), Sun Yat-sen University (CN), Xuzhou Medical College (CN), Fudan University Shanghai Cancer Center (CN), China Power Engineering Consulting Group (China) (CN), Guangzhou Medical University (CN)
Openalex Percentile: Top 69%
Hepatocellular Carcinoma Treatment and Prognosis
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