BRG1 orchestrates diabetic corneal neuropathy via PI3K/AKT-mediated glycolytic reprogramming

Glycolytic reprogramming is a critical driver of DCN progression. BRG1 activates PI3K/AKT signaling to enhance glycolytic flux, thereby regulating DCN pathogenesis. Targeting this axis may offer novel therapeutic strategies.

Authors

Wenqu Chen
Yuyang Deng
Jianzhang Hu
Danling Liao

Institutions

Fujian Medical University (CN)
Union Hospital (CN)

Publication Details

Journal: Eye and Vision
Published: 2026-02-01
DOI: https://doi.org/10.1186/s40662-026-00474-4
Primary Topic: Retinal Diseases and Treatments
Type: article
Field-Weighted Citation Impact: 0.00

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article

BRG1 orchestrates diabetic corneal neuropathy via PI3K/AKT-mediated glycolytic reprogramming

Wenqu Chen, Yuyang Deng, Jianzhang Hu, Danling Liao

Feb 1, 2026

Eye and Vision

Retinal Diseases and Treatments

article

BRG1 orchestrates diabetic corneal neuropathy via PI3K/AKT-mediated glycolytic reprogramming

Wenqu Chen, Yuyang Deng, Jianzhang Hu, Danling Liao

February 1, 2026article en

Abstract

Eye and VisionVol. 13(1)

Fujian Medical University (CN), Union Hospital (CN)

Openalex Percentile: Top 71%

Retinal Diseases and Treatments

DOI Open Access PDF OpenAlex

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BRG1 orchestrates diabetic corneal neuropathy via PI3K/AKT-mediated glycolytic reprogramming — Wenqu Chen, Yuyang Deng, et al. · Eye and Vision (2026) | TGRS Research Map | TGRS