Simplified Knee MRI ‘Sagittal Tibial Epi-Physis (STEP)’ Shorthand for Skeletal Age Assessment in Pediatric Patients with ACL Injury
<b>Objectives:</b> To develop a simplified MRI-based shorthand assessment method, referred to as the Sagittal Tibial Epi-Physis (STEP) Shorthand, for skeletal age assessment in skeletally immature patients with anterior cruciate ligament (ACL) injuries. This study aimed to elaborate a single-plane MRI-based skeletal age estimation tool and to explore its feasibility and inter-rater reliability in comparison with existing MRI-based shorthands. <b>Methods</b>: This prospective study included 130 knee MRIs (79% males) from 97 skeletally immature patients (overall average age of 14.0 ± 2.1 years) with ACL injuries treated between February 2022 and January 2025. A new shorthand assessment method was developed based on sagittal T1-weighted MRI evaluation of the proximal tibial epiphysis. A validation cohort of 74 MRIs was independently evaluated by four raters with different levels of expertise using the STEP, Meza, and Politzer shorthand atlases. Inter-rater reliability (ICC), intra-rater agreement (Cohen's kappa), and association with chronological age (Spearman rho) were calculated. <b>Results</b>: The STEP Shorthand tool demonstrated a strong association with chronological age (rho = 0.890, <i>p</i> < 0.001) with consistent associations across sex subgroups. Inter-rater reliability was high and comparable to established MRI-based shorthands. The use of a focused sagittal T1-weighted evaluation allowed for a simplified and reproducible assessment across raters with varying experience levels. <b>Conclusions</b>: The STEP Shorthand represents a pragmatic and reliable tool for MRI-based skeletal age assessment in pediatric and adolescent patients with ACL injuries. The STEP Shorthand can support timely decision-making in surgical planning and enhance standardization across different levels of clinical expertise.
Authors
- Yuta Nakanishi (ORCID: https://orcid.org/0000-0002-3011-0679)
- Luca Ambrosini (ORCID: https://orcid.org/0000-0003-2811-6817)
- Claudio Rossi (ORCID: https://orcid.org/0000-0001-6032-1015)
- Hikaru KAYANO
- A. Grassi (ORCID: https://orcid.org/0000-0001-9805-0265)
- Stefano Zaffagnini
- Amir Assaf
- Kyle Borque
- Emre Anil Ozbek
- Mohammad Ibra Alhalalmeh
Institutions
- Ankara University (TR)
- Methodist Hospital (US)
- Methodist Hospital (US)
- Istituto Ortopedico Rizzoli (IT)
- Osaka University Hospital (JP)
- Kobe University (JP)
- University of Bologna (IT)
- The University of Osaka (JP)
Publication Details
- Journal
- Diagnostics
- Published
- 2026-02-01
- DOI
- https://doi.org/10.3390/diagnostics16030442
- Primary Topic
- Knee injuries and reconstruction techniques
- Type
- article
- Field-Weighted Citation Impact
- 0.00