GC-MS Correlated-Antiepileptic Screening For Probable GABA-Modulator By PTZ-Induced Acute Seizure Model In Swiss Albino Mice And Phytochemical Profiling Of Ethanol Extract Of Ficus Benghalensis
The findings suggest that the phytoconstituents of Ficus benghalensis, such as polyphenols, flavonoids, sterols and previously unidentified alkaloids, play a key role in mitigating oxidative stress, neuroinflammation and GABAergic dysfunction associated with epilepsy, which demonstrates its potential as a source of lead compound for new antiepileptic drugs. Detailed investigations on isolated phytochemicals can be done to explore their antiepileptic potential.
Authors
- Md. Mohaimenul Islam
- Sulaman Yaqub
- Abrar Ahmad
- Hamid Saeed
Institutions
- University of the Punjab (PK)
Publication Details
- Journal
- Pakistan Journal of Pharmaceutical Sciences
- Published
- 2026-01-28
- DOI
- https://doi.org/10.36721/pjps.2026.39.3.reg.14501.1
- Primary Topic
- Phytochemistry and biological activities of Ficus species
- Type
- article
- Field-Weighted Citation Impact
- 0.00